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Scientific Publications

Contributing to and advancing the scientific dialogue.

May 2023

Phase 1 study of the pan RAF inhibitor tovorafenib in patients with advanced solid tumors followed by dose expansion in patients with metastatic melanoma

Rasco DW, Medina T, Corrie P, Pavlick AC, Middleton MR, Lorigan P, Hebert C, Plummer R, Larkin J, Agarwala SS, Daud AI, Qiu J, Bozon V, Kneissl M, Barry E, Olszanski AJ. [published online ahead of print May 23, 2023]. Cancer Chemother Pharmacol. 2023;92:15-28.

May 2023

Chart audit in pediatric low-grade glioma: molecular testing and treatment patterns

David Lee, Jorge Caravia, Kevin Lam, Judith Kulich, Katie Blodget, Sandya Govinda Raju 2023 ASPHO Conference: Poster 261

May 2023

pLGG disease burden and healthcare utilization: linked claims and EHR data study

Tabitha Cooney, Sandie Yu, Shailaja Daral, Blake Krebs, Riddhi Markan, Michelle A Field, Mark Kieran, Sandya Govinda Raju, Susan Zelt 2023 ASPHO Conference: Poster 258

April 2023

Clinical activity of the type II pan-RAF inhibitor tovorafenib in BRAF-fusion melanoma

Jeeyun Lee, MD, Natraj R. Ammakkanavar, MD, Aprajita Saini, MS, Mark W. Kieran MD, PhD, Lisa M. Kopp, DO, MPH, Bert H. O’Neil, MD 19th EADO Congress 2023: Paper #174

November 2022

FIREFLY-1 (PNOC026): Phase 2 study of pan-RAF inhibitor tovorafenib in pediatric and young adult patients with RAF-altered recurrent or progressive low-grade glioma or advanced solid tumors

Kilburn L, Landi D, Leary S, Ziegler DS, Baxter P, Franson A, McCowage G, Waanders AJ, Van der Lugt J, Oren MY, Gerber NU, Gottardo NG, Khuong-Quang D-A, Nysom K, Bailey S, Hernáiz Driever S, Perreault S, Witt O, Hahn S, Hargrave D, Hassall T, Jabado N,Kang HJ, Larouche V, Toledano H, Kline C, Abdelbaki MS, Chi SN, Gardner SL, Whipple N, Mueller S, Blackman, SC, Zhao X, Da Costa D, Cox MC, Packer R, Hansford JR 2022 Society for Neuro-Oncology – Annual Meeting 2022 SNO Annual Meeting: Abstract CTNI-68

November 2022

LOGGIC/FIREFLY-2: A phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric patients with newly diagnosed low-grade glioma harboring an activating RAF alteration

van Tilburg CM, Jones DTW, Schmidt R, Avula S, Schouten-van Meeteren A, Sehested A Opocher E, Hernáiz Driever P, Witt R, Ziegler DS, Blackman SC, Zhao X,Tsao L-P,Manley P,Cox MC, Hargrave D, Witt O 2022 Society for Neuro-Oncology – Annual Meeting 2022 SNO Annual Meeting: Abstract CTNI-30

June 2022

FIREFLY-1 (PNOC 026): A phase 2 study to evaluate the safety and efficacy of tovorafenib (DAY101) in pediatric patients with RAF-altered recurrent or progressive low-grade glioma or advanced solid tumors

Landi D, Ziegler DS, Franson AT, Baxter PA, Leary SES, Larouche V, Waanders AJ, van der Lugt J, McCowage G, Jabado N, Cornelio I, Blackman SC, Da Costa D, Cox MC, Witt O, Kilburn L, Hansford JR. ASCO Annual Meeting 2022: Abstract TPS10062

November 2021

Activity of pan-RAF inhibitor DAY101 in a pediatric patient with a recurrent spindle cell sarcoma harboring a novel SNX8-BRAF gene fusion

Offer K, McGuire M, Venetsanakos E, Blackman S, Song K, Goldfischer M, Cox M 2021 Connective Tissue Oncology Society Annual Meeting

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